Biomedical jobs in Cape Town, Western Cape
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- Reports to: Senior Director, Clinical Laboratory Operations & Immunology.
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Job Post Details
Senior Scientist, Antibody Translational Research - job post
Job details
Job type
- Permanent
Full job description
Job Title: Senior Scientist, Antibody Translational Research
Location: Cape Town, South Africa; Remote - South Africa
Reports to: Senior Director, Clinical Laboratory Operations & Immunology
POSITION SUMMARY:
Help IAVI translate science into global health impact as a Senior Scientist!
IAVI is seeking a Senior Scientist, Antibody Translational Research to lead innovative antibody research programs that advance global health while building sustainable scientific capacity across Africa.
The Senior Scientist, Antibody Translational Research is responsible for the conceptualization, development, and execution of preclinical and translational research activities advancing antibody science at IAVI. The Senior Scientist executes their responsibilities in partnership with strategic, technical, and programmatic leads within the Discovery Science team at IAVI. The Senior Scientist will work extensively with IAVI’s Global Clinical Laboratory Operations and Immunology teams, as well as the network of partnered research institutions across East and Southern Africa. The Senior Scientist designs programming to promote innovation, technical rigor, and collaboration to establish sustainable research platforms within the antibody research community in Africa. The Senior Scientist aligns the antibody translational research agenda with the conceptualization and implementation of novel research activities, building and nurturing partnerships as part of this process and assisting and advising stakeholders on technical and programmatic matters to ensure successful delivery.
KEY RESPONSIBILITIES:
Scientific leadership in antibody translational research
- Serve as conceptual and technical scientific lead in the development and implementation of high-quality translational research programs, with a focus on translational research advancing pediatric indications for HIV broadly neutralizing antibodies (bnAbs)
- Analyze and interpret relevant virological and antibody datasets to guide selection of antibody lead candidates and further antibody product development strategy
- Prepare manuscripts, reports, and scientific presentations on antibody research
- Curate and quality-control IAVI monoclonal antibody sequence datasets and associated metadata
- Harmonize antibody nomenclature and lineage annotations to curate existing IAVI datasets
Scientific strategy, proposal development and grant writing
- Communicate scientific strategy to internal and external stakeholders and support long-term scientific independence planning
- Draft and refine concept notes and grant proposals for the advancement of human immunology discovery science
- Define primary, secondary, and exploratory scientific objectives and support development of study synopses and analytical plans
- Coordinate internal scientific reviews and finalize grant submissions
- Support donor engagement and provide scientific justification for proposed programs
- Represent IAVI-affiliated research at scientific meetings and conferences
Africa hub development and capacity building
- Establish and strengthen antibody discovery and clinical immunology research capacity in East and Southern Africa by serving as a scientific liaison, maintaining and growing strategic partnerships with new and existing collaborating African research institutions
- Tailor and deliver scientific training programs; mentor early-career researchers and technical staff
- Support assay development, technology transfer, standardization, and adoption of best practices
- Build partnerships with regional research institutions to strengthen regional R&D ecosystems
EDUCATION AND WORK EXPERIENCE:
- A Ph.D. in Immunology or Virology or equivalent is required.
- Minimum 5 years’ work experience in a medical/ academic/research environment is required; experience in translational immunology research is preferred.
- Experience in immune assays such as Flow Cytometry, ELISA, B-cell and/or T-cell responses evaluation, as well as Molecular Biology is required.
- Experience with post-graduate student supervision and mentorship is required.
QUALIFICATIONS AND SKILLS:
- A proven research track record accompanied by a good publication record in the field of HIV translational science is required.
- Experience in managing multi-center research projects is required.
- Proven success in medical/academic research management and administration.
- Proven success in servicing committees.
- Excellent planning, project management, and organizational skills to multitask and prioritize.
- Excellent reasoning and analytical skills.
- Ability to establish and maintain good working relationships at all levels.
- Excellent verbal, written and presentation skills are required.
- Computer literacy, with advanced Microsoft Office skills, is required.
- Previous work experience in the field of Global Health and/or HIV is desirable.
- Proven experience in project MEL is desirable.
- Willingness to travel up to 10% is required.
Organizational Overview:
IAVI is a nonprofit scientific research organization dedicated to addressing urgent, unmet global health challenges including HIV and tuberculosis. Our mission is to translate scientific discoveries into affordable, globally accessible public health solutions. Through scientific and clinical research in Africa, India, Europe, and the U.S., IAVI is pioneering the development of biomedical innovations designed for broad global access. We develop vaccines and antibodies in and for the developing world and seek to accelerate their introduction in low-income countries. IAVI programs and partnerships are grounded in the regions of the world where the disease burden is the greatest, and our approach emphasizes sustainability. Our network of clinical research center partners in Africa and India helps strengthen in-country research capacity and supports the training and education of the next generation of scientists. The global impact of our science includes fundamental contributions to understanding the biology of HIV infection, which IAVI and others are applying toward advancing vaccine science and immunology. IAVI accelerates scientific discovery and development by fostering unique collaborations among academia, industry, local communities, governments, and funders to explore new and better ways to address public health threats that disproportionately affect people living in poverty. Our global reach, including a clinical research network in five countries in sub-Saharan Africa and in India, has allowed us to make fundamental contributions to understanding the epidemiology, transmission, virology, and immunology of HIV. This work played a key role in facilitating the design of promising HIV vaccine candidates, as well as the discovery of broadly neutralizing antibodies that are now being advanced as promising approaches for HIV prevention. Our integrated capabilities in vaccine and antibody discovery, development, and clinical research take advantage of bio-pharmaceutical industry expertise to accelerate the development and testing of prevention methods for HIV and other diseases. Through the Product Development Center, we support external researchers with technical and scientific expertise to accelerate the development of their own products.
IAVI CORE VALUES:
- Commitment: We deliver on our mission, proactively transforming promises into tangible results
- Stewardship: We steward IAVI's resources responsibly to ensure IAVI's long-term success and global health impact
- Integrity: We uphold strong moral principles to maintain our credibility as a nonprofit scientific research organization
- Collaboration: We work as one IAVI team and partner with others to deliver globally accessible, urgently needed, public health solutions
Disclaimer: Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time. The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of personnel so classified. This document does not create an employment contract, implied or otherwise, other than an “at-will” relationship. IAVI is an equal opportunity employer and applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
IAVI IS AN EQUAL OPPORTUNITY EMPLOYER actively committed to fostering a diverse and inclusive global organization. IAVI believes that diversity and inclusion among our teammates is critical, and we seek to recruit, develop and retain the most talented people from a representative candidate pool. At IAVI, we celebrate the spectrum of colleagues’ experiences and believe that dedication to our mission above all is essential to our success as a scientific global non-profit. IAVI upholds these principles through IAVI’s Global Diversity and Inclusion Committee.
Compensation And Benefits Information:
Salary is paid in local currency, and is commensurate and competitive with the local labor market. Please note, there may be some variation based on experience level. In addition, this position offers competitive benefits including: generous retirement savings plan employer contributions; competitive health, dental and vision insurance plans; competitive paid time off policy; potential for annual bonuses based on performance; and other benefits. More information can be found on IAVI's career page.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.